Delta agent (Hepatitis D)

Hepatitis D infection involves a defective viral agent that causes symptoms only in association with hepatitis B infection.

Alternative Names

Hepatitis D virus

Causes, incidence, and risk factors

Hepatitis D virus may increase the severity of an acute hepatitis B infection, aggravate previously existing hepatitis B liver disease , or cause symptoms in previously asymptomatic hepatitis B carriers. Hepatitis D infects about 15 million people worldwide, occuring in 5% of people with hepatitis B. Risk factors include the following:

  • Previous hepatitis B infection
  • Being a carrier of hepatitis B
  • Receiving many blood transfusions
  • Intravenous
  • drug abuse

    Signs and tests

  • Liver enzymes are elevated.
  • Anti-delta agent antibody
  • is positive.
  • Liver biopsy
  • shows
  • acute hepatitis .

    Treatment

    Treatment is the same as for hepatitis B .

    Expectations (prognosis)

    Expectations are similar to those of acute hepatitis B. The acute illness usually subsides over 2 to 3 weeks, and the liver enzyme levels return to baseline within 16 weeks. About 10% of people infected may develop chronic hepatitis.

    Complications

  • chronic active hepatitis
  • fulminant
  • hepatitis

    Calling your health care provider

    Call for an appointment with your health care provider if symptoms of hepatitis B occur.

    Prevention

    Prompt recognition and treatment of hepatitis B infection can help prevent hepatitis D. Avoid intravenous drug abuse. If IV drugs are used, avoid sharing needles. There is a vaccine available to prevent hepatitis B and should be considered by people who are at risk due to IV drug use, exposure to blood products, or sexual behaviors.

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